Antibodies

Antibodies are proteins that protect you when an unwanted substance enters your body. Produced by your immune system, antibodies bind to these unwanted substances in order to eliminate them from your system. Another word for antibody is immunoglobulin.

MONOCLONAL

Anti-AGE Antibody, Carboxy-Methyl Lysine Antibody, clone 6C7
Description

Chronic accumulation of Advanced Glycation End products (AGEs) is a common feature during aging, hyperlipidemia, and diabetes and affects function of proteins, lipids, and DNA.

Specifications
Isotype

IgG2ak

Form

Format: Purified Protein G purified

Storage

2-8°C

Anti-AGE Antibody, Methylglyoxal Antibody, clone 3D11
Description

Chronic accumulation of Advanced Glycation End products (AGEs) is a common feature during aging, hyperlipidemia, and diabetes and affects function of proteins, lipids, and DNA. Although formation of AGE products is considered to be predominantly an endogenous process, certain external factors, such as some dietary products and smoking can increase the level of AGE in tissues.

Specifications
Isotype

IgG2aλ

Form

Format: Purified Protein G purified Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage

Stable for 1 year at 2-8°C

Anti-CD57 antibody [NK1], prediluted
Description

Anti-CD57 antibody [NK1], prediluted

Specifications
Conjugate

Unconjugate

Isotype

IgM

Form

Liquid.

Storage

Store at +4°C.

Anti-CRABP2 Antibody
Description

Reacts with Cellular Retinoic Acid Binding Protein II (CRABPII). No cross reactivity with CRABPI.

Specifications
Isotype

IgG2a

Anti-GT1b Ganglioside Antibody
Description

GT1b ganglioside. Stains myelinated motor and sensory axons in spinal roots and peripheral nerves.

Specifications
Isotype

IgG2b

Form

Ascites Liquid. Contains no preservative.

Storage

-20°C

Anti-HEF1/NEDD-9 antibody
Description

Mouse monoclonal [2G9] to HEF1/NEDD-9

Specifications
Concentration

50 µg at 1 mg/ml

Conjugate

Unconjugate

Isotype

IgG1

Form

Liquid.

Storage

Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Anti-IKKγ Antibody
Description

IKKγ/IKK3 is also known as NEMO, FIP-3 and IKKAP-1

Specifications
Isotype

IgG

Form

Format: Purified PBS, pH 7.4, containing 0.05% sodium azide Protein G Chromatography

Storage

-20°C

Anti-Ki67 antibody
Description

Rabbit monoclonal [SP6] to Ki67

Specifications
Concentration

Batch dependent within range: 100 µl at 0.029 – 0.031 mg/ml
Batch dependent within range: 1 ml at 0.03 – 0.031 mg/ml
Batch dependent within range: 500 µl at 0.03 – 1.154 mg/ml

Conjugate

Unconjugate

Isotype

IgG

Form

Liquid.

Storage

Anti-Neurocan Antibody
Description

Neurocan is the major soluble chondroitin sulfate proteoglycan in the brain. It is thought to play a functional role in axonal growth and guidance and in the establishment of specific neural pathways during embryonic brain development.

Specifications
Isotype

IgG1

Anti-NF-kB p65 antibody
Description

Mouse monoclonal [27F9.G4] to NF-kB p65

Specifications
Concentration

50 µg at 1 mg/ml

Conjugate

Unconjugate

Isotype

IgG2a

Form

Liquid.

Storage

Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Anti-Nicastrin Antibody
Description

Nicastrin.

Specifications
Isotype

IgG2b

Storage

2-8°C

Anti-NMDAR2B Antibody
Description

NMDAR2B, N-terminal. By Western blot the antibody reacts with bands at ~170 and ~48 kDa on rat brain lystate. An additional band at ~100 kDa may be seen depending on sample and antibody concentration used.

Specifications
Isotype

IgG1

Form

Liquid

Storage

-20°C

Anti-Otx1 Antibody
Description

Otx1

Specifications
Isotype

IgG1

Form

Liquid

Storage

-20°C

Anti-Parvalbumin Antibody
Description

Parvalbumin is a calcium binding albumin protein. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is localised in fast-contracting muscles, where its levels are highest, and in the brain and some endocrine tissues. Parvalbumin is present in GABAergic interneurons in the nervous system, predominantly expressed by chandelier and basket cells in the cortex.

Specifications
Isotype

IgG1

Form

Ascites mouse monoclonal IgG1 liquid Unpurified

Anti-Phosphacan Antibody
Description

Phosphacan is a soluble nervous tissue-specific proteoglycan that is thought to regulate axonal outgrowth. It is synthesized by glia and binds to neurons and to the neural cell adhesion molecules tenascin, N-CAM or NG-CAM but not to laminin and fibronectin. Phosphacan acts as a potent inhibitor of cell adhesion and neurite outgrowth.

Specifications
Isotype

IgM

Form

Liquid

Storage

-20°C

Anti-PPAR α Antibody
Description

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that can be activated by a variety of compounds including fibratus, thiazolidinediones, prostaglandins and fatty acids. Three PPAR subtypes, designated PPARα, PPARβ (also designated PPARδ) and PPARγ, have been described. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARα is abundant in primary hepatocytes where it regulates the expression of proteins involved in fatty acid metabolism. PPARβ is the most widely distributed subtype and is often expressed at high levels. PPARγ is predominantly seen in adipose tissue where it plays a critical role in regulating adipocyte differentiation.

Specifications
Isotype

IgG2a

Form

Liquid

Storage

-20°C

Anti-TCL1 Antibody
Description

TCL1A, no cross-reactivity with TML1 (TCL1B) or MTCP1

Specifications
Isotype

IgG

Form

Cell culture supernatant

Storage

-20°C

Anti-V5 antibody, Mouse monoclonal
Description

Monoclonal Anti-V5 is derived from the V5-10 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with a synthetic peptide conjugated to KLH.

Specifications
Concentration

~1 mg/mL

Conjugate

unconjugated

Isotype

IgG1

Form

Liquid

Storage

store at 2-8 °C

CMV pp65 MONOCLONAL ANTIBODY
Description

Specifications
Isotype

IgG

Form

Format: Purified One dropper vial containing 5 mL of a blend of monoclonal antibodies specific for cytomegalovirus (CMV) pp65 antigen in buffer containing protein stabilizer, and 0.1% sodium azide (preservative). Protein A purified

Storage

2-8°C

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